EPIZYME, INC.

In Program Year 2024, EPIZYME, INC. reported $8,122,556.33 in payments to 46 physicians and teaching hospitals across 2,516 individual transactions — an average of $3.2K per transaction and $176.6K per recipient. That total places EPIZYME, INC. at rank #193 out of 1,797 companies in the CMS Open Payments database, representing 0.1% of all industry payments reported nationwide for the year. Payment volume at this scale is characteristic of manufacturers with broad prescriber engagement, active clinical research programs, or patented therapies generating ongoing royalty obligations.

The payment mix for EPIZYME, INC. spans 2 distinct categories defined by CMS — including general payments (consulting, speaker fees, meals, travel), research payments tied to clinical trials, and ownership or investment interests. The largest single category is "Consulting Fee" at $15.4K, accounting for 0.2% of the company's reported total and 7 transactions. This distribution matters because different payment types carry different regulatory and ethical implications: research funding supports clinical development, while general payments like meals and speaker fees have been studied for their correlation with prescribing patterns in peer-reviewed journals such as JAMA Internal Medicine.

Recipient concentration is another useful lens. The top 5 recipients of payments from EPIZYME, INC. received $0.00 combined — 0.0% of the company's total — with the remaining 100.0% distributed across the rest of the 46 recipients. A relatively distributed top-5 share suggests broader engagement across the prescriber community rather than concentration among a handful of high-value relationships. All figures above are drawn directly from the CMS Open Payments Public Use Files for PY2024 and are disclosed under the Physician Payments Sunshine Act; this page summarizes reported financial transfers and does not represent medical advice or judgment about individual prescribing decisions.